FORNEUROCELL - Projects

• (Re)programming of neural progenitor cells
  • Development of a methodology to differentiate human astrocytes into functional neurons
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• Characterizing and establishing of adult human neural stem cells
  • Characterisation of adult stem cells of the human hippocampus
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  • Characterization and mobilization of adult neural stem cells to induce cellular regeneration in Parkinson’s disease
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  • Identification of signalling pathways in the induction, differentiation and conservation of dopaminergic neurons in the embryonal and adult mid-brain.
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• Establishing and implementing innovative imaging techniques to detect endogenous neurogenesis and grafted cells
  • In vivo cell tracking by magnetic resonance tomography (MRT) of adult neural stem cells and brain parechyma response to stem cell transplantation
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  • Optical and MR imaging tools to track neural stem and precursors cells in adult brains
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• Identification of signalling pathways and receptor structures that may serve as targets to modulate neural stem cells
  • Characterization and mobilization of adult neural stem cells to induce cellular regeneration in Parkinson’s disease
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  • Co-transplantation of adult neural progenitor cells and mesenchymal stromal cells to promote axonal regeneration und remyelination in the injured spinal cord
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  • Identification of signaling-pathways regulating adult neural stem cell maintenance
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  • Identification of signalling pathways in the induction, differentiation and conservation of dopaminergic neurons in the embryonal and adult mid-brain.
    more
• Mobilization of endogenous neural stem cells
  • Characterization and mobilization of adult neural stem cells to induce cellular regeneration in Parkinson’s disease
    more
• Pre-clinical testing in acute and chronic lesion models
  • Characterization and mobilization of adult neural stem cells to induce cellular regeneration in Parkinson’s disease
    more
  • Co-transplantation of adult neural progenitor cells and mesenchymal stromal cells to promote axonal regeneration und remyelination in the injured spinal cord
    more
  • Development of a methodology to differentiate human astrocytes into functional neurons
    more
  • Identification of signaling-pathways regulating adult neural stem cell maintenance
    more
  • Identification of signalling pathways in the induction, differentiation and conservation of dopaminergic neurons in the embryonal and adult mid-brain.
    more
  • In vivo cell tracking by magnetic resonance tomography (MRT) of adult neural stem cells and brain parechyma response to stem cell transplantation
    more
  • Optical and MR imaging tools to track neural stem and precursors cells in adult brains
    more