FORPROTECT
BAVARIAN RESEARCH ASSOCIATION FOR INFECTION PROTECTION BY MEANS OF NEW DIAGNOSTIC AND THERAPEUTIC METHODS
I4 - Replicon-Technology for Assessment and Production of Adenoviruses with a High Security Profile
Based on a newly developed replicon vector system for the complementation of herpesviruses, a similar replicon system is to be evaluated in regards to its suitability for the production of adeno viral vectors. These new vectors will be able to be replicated as well as first generation vectors but with a higher safety profile. This technology is to be used for the production of serotype vectors for clinical use and tested as a new platform for the detection of virus infections.