FORINGEN

RESEARCH NETWORK FOR INFECTOGENOMICS

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Vaccines and Adjuvants

Vaccinations are the most effective and low-prized protection against infectious diseases. And many principles in immunization may also be valid for the treatment of tumors. To achieve an efficient immune response different strategies are pursued: viral or bacterial gene vectors can help to specifically target immune cells and elicit an immune response; DNA vaccines can mimic a real virus infection. A novel approach is the so called reverse vaccinology. Researchers analyze the genomic sequence of a pathogen on a computer to identify proteins that can be useful for immunization. The scientists in the research network FORINGEN aim to develop vaccination strategies against hepatitis C virus, herpes viruses and chlamydiae, which cause severe infection of the eye and other organs.

Projects

  • VA-2 Development of a therapeutic T-cell vaccine against Hepatitis C Virus (HCV)
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  • VA-4 Genome-based vaccine strategies against HIV
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  • VA-5 Reverse vaccinology against chlamydial infections
    more
  • VA-6 Bacteria and cancer
    more

Information

Launching date

12.2005

End

11.2008

Funded by

Bavarian Research Foundation