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VA-5 Reverse vaccinology against chlamydial infections Chlamydia are bacteria, which need to invade host cells for their replication, i.e. they grow within cells and are therefore less accessible…

VA-4 Genome-based vaccine strategies against HIV Despite of excessive financial and scientific efforts, there is still no control of the HIV pandemic. Up to date, the development of effective…

VA-2 Development of a therapeutic T-cell vaccine against Hepatitis C Virus (HCV) The chronic infection with Hepatitis C Virus (HCV), which is a RNA virus belonging to the family of flaviviruses,…

DT-8 HIV-1 Vpr as a target for antiviral therapy Since the beginning of the 1980s millions of people have been infected with human immunodeficiency virus type 1 (HIV-1), the causative agent of the…

DT-6 Antibiotic resistance of Pseudomonas aeruginosa from Cystic Fibrosis patients Cystic fibrosis (CF) is the most common autosomal recessive disease in the Caucasian population arising from…

DT-5 Development of a Microsphere based multiplex serology for differential diagnosis in reactive arthritis and lyme arthritis. Bacterial infections can cause apart from their typical acute, febrile…

DT-4 Genome-based identification of targets specific for bovine Staphylococcus aureus isolates Staphylococcus aureus is one of the most important causes of bovine mastitis causing significant health…

DT-3 H. pylori pathodiagnostics Epidemiological data suggest that the bacterial pathogen Helicobacter pylori infects about 20 Mio. German citizens. Infection is mostly asymptomatic, but 10-15% of…

DT-1 Improvement of a DNA array for diagnostics of clinically relevant enterobacteria Enterobacteria comprise a variety of non-pathogenic, commensal variants, which belong to the normal gut flora of…